Daniel Gibson scored 17 of his 22 points in the fourth quarter, while Anderson Varejao added 23 points and 12 rebounds to help the Cavaliers win their eighth straight game in Philadelphia, 123-116.
Mo Williams notched 22 points to go with seven assists, and J.J. Hickson donated 16 points and eight caroms for Cleveland, which had lost three straight since a season-opening win over Boston.
Jrue Holiday scored a career-high 29 points and handed out eight assists for Philadelphia, which erased a 19-point first half deficit and led by eight in the final quarter before faltering down the stretch.
The Sixers, losers in five of six to start the year, also lost the versatile Andre Iguodala to a strained right Achilles tendon.
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